We are advancing new chemical probing, sequencing, and bioinformatics technologies that will reveal and define functional RNA-protein interaction networks inside cells. We are also interested in developing technologies to target these networks. (R01GM155542) 

We are applying multi-omics approaches to understand long noncoding RNAs that promote cancer progression and metastasis (NCI K22 CA262349). Image adapted from publication here. 

We are defining substrate specificities of RNA-modifying enzymes inside cells and applying multi-omics and reporter assays to understand these molecular switches.